Resumen
Background: Procedure-related bleeding remains a common complication after endoscopic diverticulectomy of intraluminal duodenal diverticulum (IDD). The optimal endoscopic approach to IDD has not been established. Platelet-rich plasma (PRP) has proven
biological properties to reduce risk of bleeding.
Materials and Methods: The authors describe a novel technique in which endoscopic diverticulectomy was performed with prior
submucosal injection of PRP (IRB approval PT-16-002).
Case Report: A 62-year-old woman with a large IDD like a “windsock” underwent endoscopic diverticulectomy with PRP obtained
from a sample of patient’s blood. IDD was resected with EMR technique using a standard polypectomy snare. No immediate or delayed bleeding was noted. Follow-up endoscopy 3 months later revealed complete mucosal healing and open communication to the
distal duodenum.
Conclusion: Endoscopic diverticulectomy with PRP is an option in patients with IDD
